Autonomic Nerve Involvement And Venous Leakage In Diabetic Men With Impotence

Objective To determine the neurophysiological and vascular factors in diabetic impotence, particularly the role of autonomic neuropathy on venous leakage and erectile impotence.Patients and methods Thirty-four diabetic men with impotence were investigated using Various neurophysiological and radiological methods, The results were compared with those from patients with idiopathic penile Venous leakage for autonomic neuropathy, especially for spontaneous cavernosal activity (SCA).Results Of the neurophysiological tests, the SCA was most frequently abnormal, with the loss of normal periodic oscillations, Penile venous leakage, either alone or with arterial insufficiency, was the most frequent vascular problem (67%) in patients with diabetic impotence, in whom the SCA was absent in most (83%). Conversely, the SCA was normal in all impotent patients with idiopathic venous leakage.Conclusion Venous leakage in diabetic patients is probably produced by autonomic dysfunction of the penile vascular innervation or degeneration of penile smooth muscles, because the SCA was absent more often in these patients.