The Effect of Aging and Caloric Restriction on Murine CD8+ T Cell Chemokine Receptor Gene Expression

Raymond Yung,RuRan Mo,Annabelle Grolleau-Julius,Mark Hoeltzel

Immunity & ageing（2007）

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摘要

The mechanism explaining the increased disease susceptibility in aging is not well understood. CD8+ T cells are crucial in anti-viral and anti-tumor responses. Although the chemokine system plays a critical role in CD8+ T cell function, very little is known about the relationship between aging and the T cell chemokine system.

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关键词

Chemokine Receptor,Caloric Restriction,CCR7 Expression,Chemokine Receptor Expression,Cell CCR1

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