2.2 Mb Of Contiguous Nucleotide-Sequence From Chromosome-Iii Of C-Elegans

Richard K Wilson,R. Ainscough,K J Anderson,Caroline Baynes,M. Berks,James K Bonfield, Jeremy B Burton, Mary A O Connell,T. Copsey,John Cooper, A R Coulson,Molly Craxton,Simon Dear,Z. Du,Richard Durbin,A. Favello,A R Fraser,Lucinda Fulton, Andrew Gardner, Peter D Green, T. Hawkins,Ladeana W Hillier, M. Jier, L A Johnston, M. Jones, J K Kershaw, J. Kirsten, N. Laisster,Paul L Latreille, J. Lightning, Chelsea R Lloyd, B. Mortimore,M. O'Callaghan, Joshua B Parsons, C. Percy, L. Rifken,Avtar Roopra, D M Saunders,R. Shownkeen, Mark R Sims, N. Smaldon, A J S Smith,M. Smith,Erik L L Sonnhammer,Rodger Staden,John E Sulston,Jean Thierrymieg, Karen Thomas,M D Vaudin,Kevin T Vaughan,Robert H Waterston,A T Watson, L A Weinstock, J. Wilkinson-Sproat, P. Wohldman

Nature(1994)

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摘要
As part of our effort to sequence the 100-megabase (Mb) genome of the nematode Caenorhabditis elegans, we have completed the nucleotide sequence of a contiguous 2,181,032 base pairs in the central gene cluster of chromosome III. Analysis of the finished sequence has indicated an average density of about one gene per five kilobases; comparison with the public sequence databases reveals similarities to previously known genes for about one gene in three. In addition, the genomic sequence contains several intriguing features, including putative gene duplications and a variety of other repeats with potential evolutionary implications.
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关键词
genome sequence,base pair,gene duplication,nucleotide sequence,gene cluster
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