Immunosuppression for Myelodysplastic Syndrome: How Bench to Bedside to Bench Research Led to Success
Hematology/Oncology Clinics of North America(2010)
摘要
Laboratory evidence and clinical evidence suggest that some patients with myelodysplastic syndrome (MDS) have immunologically mediated disease. This article describes the laboratory evidence supporting a role for the immune system in the marrow failure of MDS and clinical trials using IST in these patients.
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关键词
Immunosuppression,Myelodysplastic syndrome,Tumor necrosis factor,IFNγ
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