A Scaleable Formal Total Synthesis of Dehydrogliotoxin

Travis C. McMahon,Sarah Stanley,Edward Kazyanskaya,Deborah Hung,John L. Wood

Tetrahedron letters（2011）

引用 12|浏览5

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摘要

A formal total synthesis of the epidithiodiketopiperazine natural product, dehydrogliotoxin (2), utilizing an intramolecular ring closure to form key intermediate 5 is described.

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关键词

Gliotoxin,Dehydrogliotoxin,Diketopiperazine,Formal synthesis

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