Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase.
Bioorganic & Medicinal Chemistry Letters（2006）
摘要
The synthesis and SAR studies of oxazepines, thiazepines, and diazepines as novel EGFR inhibitor classes are reported.
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关键词
Epidermal growth factor receptor,Kinase inhibitor,Oxazepine,Diazepine,Thiazepine
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