Depressive Symptoms And Depo-Provera (R)

Women enrolled in a multicenter prospective study were evaluated to identify any possible relationship between depressive symptoms and the use of contraceptives. Women choosing Depo-Provera(R) (n = 495) were evaluated before starting these contraceptives and were reinterviewed 1 year later. Women who continued she method had lower depressive symptom scores at baseline than did the women who discontinued the method or who were lost to follow-up. Among the continuing Depo-Provera users, the depressive symptom scores improved slightly at 1 year (7.4 vs 6.7). Those subjects with the highest (ie, worst) scores at enrollment demonstrated improved scores at follow-up. CONTRACEPTION 1998;57:237-240 (C) 1998 Elsevier Science Inc. All rights reserved.