Ursodeoxycholic acid prevents hepatic cytochrome P450 isozyme reduction in rats with deoxycholic acid-induced liver injury

M Tanaka,H Nakura,T Tateishi,M Watanabe,S Nakaya,T Kumai,S Kobayashi

Journal of Hepatology（1999）

引用 16|浏览16

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摘要

Background/Aims: Hydrophobic bile acids, such as deoxycholic acid produce cholestatic liver injury. Ursodeoxycholic acid has been shown to be useful in the treatment of cholestatic liver disease.

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关键词

Bile acids,Cytochrome P450,Deoxycholic acid,Drug-metabolizing system,Liver injury,Ursodeoxycholic acid

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