Calcium oscillation and phosphatidylinositol 3-kinase positively regulate integrin α<sub>IIb</sub>β<sub>3</sub>-mediated outside-in signaling

Journal of Biomedical Science, Volume 12, Issue 2, 2005, Pages 321-333.

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phosphatidylinositol 3-kinaseintegrin outside-in signalingcalcium oscillationintegrin aiibb3

摘要

Summary The frequency of calcium oscillation reveals the platelet activation status, however, the biological significance of the periodic calcium responses and methods of communication with other integrin-mediated signals are not clear. RGD-containing disintegrin rhodostomin coated substrates were employed to enhance platelet spreading an...更多

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