Calcium oscillation and phosphatidylinositol 3-kinase positively regulate integrin α<sub>IIb</sub>β<sub>3</sub>-mediated outside-in signaling
Journal of Biomedical Science, Volume 12, Issue 2, 2005, Pages 321-333.
phosphatidylinositol 3-kinaseintegrin outside-in signalingcalcium oscillationintegrin aiibb3
Summary The frequency of calcium oscillation reveals the platelet activation status, however, the biological significance of the periodic calcium responses and methods of communication with other integrin-mediated signals are not clear. RGD-containing disintegrin rhodostomin coated substrates were employed to enhance platelet spreading an...更多