An improvement on water absorbing and permeating properties: Heparin immobilizing on acrylic acid-grafted and collagen/chitosan-immobilized wound dressing

Various concentrations of heparin were employed in this study to immobilize on the acrylic acid-grafted and collagen/chitosan-immobilized polypropylene (PP-AAg-CCi) nonwoven fabric to improve the water absorbing and permeating properties. The immobilized heparin was verified by analyzing of the spectra of surface reflection infrared spectroscopy. It was found that the values of water absorbing and water diffusion coefficient for the PP-AAg-CCi sample immobilized with heparin (PP-AAg-CCHi) were significantly higher than those for the PP-AAg-CCi. The bacteria inhibition percentage and bacteria inhibition zone for the PP-AAg-CCHi were excellently. The pore and agent distribution for PP-AAg-CCi were examined with scanning electron microscope photographs. (C) 2008 Wiley Periodicals, Inc.