Dysregulated TCL1 requires the germinal center and genome instability for

Text Pages: 29 Figures: 7 Tables: 1 Words in Abstract: 200 Total Words:4,975 Abbreviations: AICDA, activation-induced cytidine deaminase; BCR, B cell antigen receptor; BL, Burkitt lymphoma; BLL, Burkitt-like lymphoma; Chr, chromosome; CSR, class switch recombination; DLBCL, diffuse large B cell lymphoma; FL, follicular lymphoma; GC, germinal center; MMHCC, mouse models of human cancer consortium; NHL, non-Hodgkin lymphoma; PNA, peanut agglutinin; SHM, somatic hypermutation; SKY, spectral karyotype; TCR, T cell antigen receptor; Ts(15), trisomy 15 Blood First Edition Paper, prepublished online May 25, 2006; DOI 10.1182/blood-2006-02-001354 Copyright © 2006 American Society of Hematology