The decay psi(2S) -> Omega(-)(Omega) over bar (+) is analyzed using 14 x 10(6) psi(2S) events recorded by the Beijing Spectrometer II (BES II) at the Beijing Electron Positron Collider (BEPC). Based upon events with no missing charged tracks and a satisfactory four-constraint kinematic fit, we determine the upper limit for the branching fraction of psi(2S) -> Omega(-)(Omega) over bar (+) to be 1.5 x 10(-4) at a 90% confidence level. By including events with one missing charged track, we are able to report the first evidence of an Omega(-)(Omega) over bar (+) signal with a statistical significance of 3.1 sigma. The branching fraction of psi(2S) -> Omega(-)(Omega) over bar (+) is determined to be (4.80 +/- 1.56(stat)+/- 1.30(sys)) x 10(-5).