Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues.

L Yang,G Morriello,K Leung,T Jacks,K Cheng,K D Schleim,R Smith,A A Patchett

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（1999）

引用 6|浏览19

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摘要

Replacement of the phenyl in 3 with a 2-pyridyl or 4-thiazolyl group resulted in increased potency in the rat pituitary cell GH release assay and in beagles, (C) 1999 Elsevier Science Ltd. All rights reserved.

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