Sheep Gene-Mapping - Assignment Of Aldob, Cyp19, Wt And Sox2 By Somatic-Cell Hybrid Analysis

Twenty-four hamster-sheep hybrid cell lines representing eleven ovine synteny groups were used to make syntenic assignments for seven loci ALDOB (aldolase B, fructose biphosphate); AMH (anti-Mullerian hormone); CYP19 [cytochrome P-450 aromatase, subfamily XIX (aromatization of androgens)]; WT (Wilms' tumour gene); SOX2 (SRY-related HMG-box gene 2); FSHB (follicle-stimulating hormone, beta polypeptide); and SRY (sex region of Y chromosome). These loci were assigned to synteny groups U11(chr2) (ALDOB); U19 (AMH); U3(chr7) (CYP19); and to chromosomes 15 (WT) and 1 (SOX2). SRY defines the hybrids containing the Y chromosome.