The Infant Behavioral Assessment and Intervention Program for very low birth weight infants at 6 months corrected age.

Objective To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP), designed to support and enhance infants' self-regulatory competence, improved developmental and neurobehavioral outcomes in very low birth weight (VLBW) infants. Study design Nile randomized 86 infants to I intervention before discharge and to 6 to 8 home interventions until 6 months corrected age, and 90 control infants received standard care. Developmental and behavioral outcomes were evaluated at 6 months corrected age with the Bayley Scales of Infant Development-II (BSID-II). Neurobehavioral functioning was evaluated with the Infant Behavioral Assessment (IBA) at baseline and at 6 months corrected age. Results Despite randomization, some differences in neonatal characteristies were found between the intervention and control infants. After adjustment, intervention effects of 7.2 points (+/- standard error 3.1.) on the Mental Developmental Index and 6.4 +/- 2.4 points on the Psychomotor Developmental Index favored the intervention infants. The Behavioral Rating Scale of the BSID-II (P = .000) and the IBA (more approach [P = .003] and less stress [P = .001] over time) also favored the intervention infants. Conclusions The IBAIP improved the mental, motor, and behavioral outcomes of VLBW infants at 6 months corrected age. (J Pediatr 2009:154:3.3-8)