Progress In Copper-Catalyzed Ullmann-Type Coupling Reactions In Water

Copper-catalyzed Ullmann-type coupling reactions have become an important powerful synthetic method in modem organic synthesis. Compared with the usually used organic solvent, employing abundant, cheap, environmental-friendly water as reaction media is obviously more fitful for green chemistry and low carbon sustainable development. The recent progress of copper-catalyzed Ullmann-type including C-N, C-O, C-S and C-C coupling reactions by using water as solvent is reviewed.