Absolutely conserved tryptophan in M49 family of peptidases contributes to catalysis and binding of competitive inhibitors
Bioorganic Chemistry（2009）
摘要
Binding of a competitive inhibitor Tyr-Phe-NHOH to the active site of human DPP III.
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关键词
Dipeptidyl peptidase III,Hydroxamate inhibitor,Peptidase family M49,Protein structure-function,Site-directed mutagenesis
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