Effect of Immune Mucosal Antibody and Serum Antibody of Newcastle Disease Used Different Immunization Approachs for Layer Chicken

In order to explore the effects of immune mucosal antibody and serum antibody of Newcastle disease used different immunization approachs for layer chicken,we used different immunization approachs immunized the commercial layer chickens.The results showed that the Newcastle mucosal antibody and serum antibody titers of chickens were significantly different after they were immunized with Newcastle disease attenuated vaccine by different immune pathways at the same time.Three times of immunization by spraying when 3-day-old,15-day-old and 25-day-old,respectively,chicken produced ND mucosal antibody and serum antibody above the protective level(6 log2) most fastly,the highest level of antibody maintained the longest time,the overall immune effect was the best.While the levels of ND mucosal antibody and serum antibody of chickens immunized by drinking water were not high,and the overall immune effect was the worst.