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Auditory Response Showing Brain Source Abnormalities in Schizophrenia

Schizophrenia research(2003)

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摘要
Traumatic brain injury is expected to become the major cause of death and disability for children and young adults by the year 2020. One of the most frequent and most morbid pathologies resulted from a head trauma is acute subdural haematoma (ASDH). For nearly one third of the ASDH cases the etiopathology directly relates to a bridging vein (BV) rupture.In the current study the bridging vein–superior sagittal sinus (BV–SSS) units were axially stretched until failure for strain rates ranging from 2.66 s−1 to 185.61 s−1, in order to investigate any strain rate dependency in their mechanical behaviour.Results showed that up to 200 s−1, the effect of the strain rate on veins' mechanical behaviour is outweighed by the large morphological intra- and inter-individual variations. Gender had a strong influence on the BVs geometrical description, but exerted no direct influence on the BV biomechanical parameters. Veins' dimensions had the strongest influence on the BV mechanical behaviour and on the failure mechanism.The present study brings important contribution to the ASDH research, emphasising the importance of considering the BV–SSS complex as a whole when trying to describe the ASDH mechanopathology.
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