Púrpura trombocitopênica idiopática e linfoma não-Hodgkin de células T na infância

Abstract Lymphomas represent 10% of all malignant tumors in childhoodand from these non-Hodgkin's lymphomas are the most frequent.Children who have autoimmune diseases have a higher probabilityof developing lymphoproliferative diseases, which can happenbefore, during or after the appearance of the neoplasia. Theassociation between idiopathic thrombocytopenic purpura andlymphomas is not common (3%) especially in children. Twotheories try to explain the origin of this association. In the firstone, the thrombocytopenia would be a result of an autoantibodyanti-blood platelet production by the tumoral clone. In the secondone, the idiopathic thrombocytopenic purpura would be a result ofa persistent antigenic stimulus subordinate to a disorder in thelymphoid proliferation. The aim of this work is to report the unusualassociation between idiopathic thrombocytopenic purpura and T-cell non-Hodgkin's lymphoma in childhood. Rev. bras. hematol.hemoter. 2006; 28 (1):73-75. Key words : Idiopathic throm bocytopenic purpura; non-Hodgkin'slymphoma; autoimmune diseases; thrombocytopenia.