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C1q and tumor necrosis factor superfamily: modularity and versatility.

Trends in Immunology, no. 10 (2004): 551-561

被引用347|浏览5
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C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of ligands via its globular (gC1q) domain and modulate immune cells, probably via its collagen region. The gC1...更多

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