SSCP Analysis of the Tyrosine Kinase Domain of the Insulin Receptor Gene: Polymorphisms Detected in South African Black and White Subjects.
Human genetics(1996)
摘要
The frequency of DNA polymorphisms in the tyrosine kinase domain (exons 17-21) of the insulin receptor gene was assessed in 30 black and 30 white South Africans, using single-stranded conformation polymorphism and direct sequencing analysis. A comparison of the frequencies of the normal versus the combined polymorphic alleles, found only in exon 17, showed a significant difference between black and white groups (P = 0.037).
更多查看译文
关键词
Internal Medicine,Tyrosine,Sequencing Analysis,Tyrosine Kinase,Metabolic Disease
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要