Fibroepithelial papillomatosis (“skin tags”) in Rabson-Mendenhall syndrome

Rabson-Mendenhall syndrome is a rare autosomal recessive syndrome in children involving a defective insulin receptor gene. Several phenotypic features are common to this syndrome, including severe hyperinsulinemia, growth retardation, acanthosis nigricans, dental dysplasia, hirsutism, coarse facial features, and pineal hyperplasia. The authors evaluated and treated a patient with Rabson-Mendenhall syndrome who presented with additional notable syndromic sequelae including extensive fibroepithelial papillomatosis (“skin tags”), not previously described to this extent.