Effects of griseofulvin on apoptosis through caspase-3- and caspase-9-dependent pathways in K562 leukemia cells: An in vitro study.

Ning Zhong,Hankui Chen,Quanlin Zhao,Hongwei Wang,Xin Yu,Ashley M Eaves,Weihua Sheng,Jingcheng Miao,Fengmei Cui,Jinzhi Wang

Current Therapeutic Research（2010）

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摘要

Background: Griseofulvin, an oral nontoxic antifungal drug, has been reported to possess anticancer effect in human cancer cells, while the mechanisms are not completely understood.

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关键词

griseofulvin,caspase-3,caspase-9,K562 cells,apoptosis

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