Epileptic seizure localized by whole head MEG

Abstract: IntroductionMagnetoencephalography (MEG) iscurrently used clinically for presurgicallocalization of epileptic tissue, based on signalsfrom interictal spikes, using single equivalentcurrent dipole (ECD) modeling [1,2,3,4]. Therehas been a long-standing question "Do interictalspikes co-localize to the same area as epilepticseizures?"Minassin, et al. found that the interictalMEG localization of spikes corresponded toictal zones mapped by the ECoG in ten ofeleven patients [5]. MEG was ...