Histopathologic And Trypsin Digestion Studies Of The Retina In Incontinentia Pigmenti

Objective: To report the ocular histopathologic features of a 55-year-old patient with incontinentia pigmenti retinopathy.Design: Observational case report.Participant. A 55-year-old patient with incontinentia pigmenti retinopathy.Methods: Examination of eyes by light microscopy and retinal trypsin digestion.Main Outcome Measures: Clinical and histopathological findings.Results: Histopathologic examination disclosed inner retinal ischemic atrophy, capillary beading, arteriolar-venous anastomoses, preretinal neovascularization, vasculopathy located at the junction of central vascular and peripheral avascular retina, retinal tears, and tractional retinoschisis.Conclusions: Patients with retinal manifestations of incontinentia pigmenti may progress to proliferative vitreoretinopathy or retinal detachment and should be observed closely over the course of their lifetime.