Dibasic non-imidazole histamine H3 receptor antagonists with a rigid biphenyl scaffold.

Bioorganic & Medicinal Chemistry Letters（2006）

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摘要

A class of rigid dibasic H3 antagonists is reported. Compound 5 with subnanomolar affinity for human H3 receptor was identified.

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关键词

Histamine,H3 receptor antagonists,Non-imidazole,Biphenyl,Dibasic

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