Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke
Bioorganic & Medicinal Chemistry Letters(2004)
摘要
Structural modifications were made to a previously described acyl dipeptide caspase inhibitor, leading to the oxamyl dipeptide series. Subsequent SAR studies directed toward the warhead, P2, and P4 regions of this novel peptidomimetic are described herein.
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关键词
Signal Peptides
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