Measurement and modeling of health-related quality of life

Health-related quality of life (HRQOL) concerns how well people are able to function and how they feel about physical, mental, and social dimensions of their lives. HRQOL data are most often collected using self-report methods of assessment (e.g., questionnaires or interviews). There are generic and targeted profile measures that yield multiple HRQOL scores as well as preference-based measures that summarize HRQOL in a single score. There are several attributes of good HRQOL measures that include a conceptual model, reliability, validity, interpretation of scores, respondent and administrative burden, alternative assessment modalities, and availability of translations. HRQOL measures are used in research, population surveillance, and in clinical practice.