Pharmaco-toxicological aspects of carcinogenic tryptophan pyrolysis products in the environment

During the last decade a new series of mutagenic and carcinogenic heterocyclic amines has been isolated from pyrolysates of amino acids and proteins. Among them carcinogenic tryptophan pyrolysis products have been investigated from various points of view, and useful pieces of information have been collected. The purpose of this report is to summarize data on carcinogenic tryptophan pyrolsis products.