Preparation of trisulfide derivatives of cystine and their formation as by-products during peptide synthesis

TETRAHEDRON LETTERS(1994)

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摘要
The formation of a trisulfide derivative is observed when di-NH2-protected cystine, is used during peptide synthesis. This side reaction occurs during the coupling step with several coupling reagents. A convenient method for the preparation of these derivatives in mild conditions is described
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