Synthesis of benz[d]indeno[1,2-b]pyran-5,11-diones: versatile intermediates for the design and synthesis of topoisomerase I inhibitors.
Bioorganic & Medicinal Chemistry Letters（2006）
摘要
A one-pot, two-step synthesis of indenopyrans and their conversion to indenoisoquinoline topoisomerase I inhibitors are reported.
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关键词
Indenoisoquinoline,Topoisomerase I inhibitor,Synthesis,Anticancer
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