Synthesis and Antimicrobial Activity of N-(Substitutedphenyl)-N '-[ 1,2,3,4-Tetrahydro-2-oxido-1,3,2-benzodiazaphosphorine-2-yl] Ureas

N-(Substitutedphenyl)-N'-[1,2,3,4-tetrahydro-2-oxido-1,3,2-benzodiazaphosphorine-2-yl] ureas 5 which are substituted ureas of the type RR'P(O)NHC(O)NR"R"' have been synthesized from reactions of 2-aminobenzylamine 2 with chlorides of arylcarbamidophosphoric acids 4 in the presence of triethylamine at 40-45 degreesC. IR, H-1 and P-31 NMR and mass spectra are recorded and analysed. The title compounds have been screened for their antifungal and antibacterial activities. All of these compounds exhibit significant activity in the assays.