Synthesis of PNU-243922 labelled with14C

C. Felicini,E. Fontana,D. Giribone,B. M. Nilsson,K. �sterlund,A. Paptchikhine

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS（2003）

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摘要

The arylpiperazine PNU-243922 (1) has been labelled with 14 C. A two-step sequence starting from the C-14 labelled alcohol 6a led to radiochemically pure (> 98%) [C-14]PNU-243922 with a specific activity of 546 MBq/mmol. Copyright (C) 2002 John Wiley Sons, Ltd.

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PNU-243922,arylpiperazine,carbon-14,anti-obesity agent

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