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Antibody-induced lysis of isolated rat epididymal adipocytes and complement activation in vivo.

Keith Dickinson,Tracey J North,Gary Telford,Susan E Smith,Bryan M Edwards,Sarah H Main,Ray Field,Diane Hatton,Tristan J Vaughan,David J Flint,Robert B Jones

Obesity research（2002）

Cited 4|Views21
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Abstract
Individual and combinations of monoclonal anti-adipocyte antibodies produced a complement-dependent and concentration-dependent activity to lyse adipocytes in vitro and in vivo as measured by a dramatic depletion in serum complement.
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