Arylacetamide κ opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity

Bioorganic & Medicinal Chemistry Letters（2005）

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摘要

Synthetic strategies to improve the selectivity of the arylacetamide class of κ opioid agonists toward CYP2D6 is reported.

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关键词

κ Opioid,CYP2D6

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