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Scaffolder - software for manual genome scaffolding

Source Code for Biology and Medicine(2012)

引用 17|浏览4
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摘要
The assembly of next-generation short-read sequencing data can result in a fragmented non-contiguous set of genomic sequences. Therefore a common step in a genome project is to join neighbouring sequence regions together and fill gaps. This scaffolding step is non-trivial and requires manually editing large blocks of nucleotide sequence. Joining these sequences together also hides the source of each region in the final genome sequence. Taken together these considerations may make reproducing or editing an existing genome scaffold difficult.
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关键词
FASTA Sequence,Unknown Region,Genome Scaffold,Scaffold Sequence,Command Line Interface
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