Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Bioorganic & Medicinal Chemistry Letters（2002）
摘要
The syntheses and pharmacological profiles of some 2-trifluoromethyl-8-methoxyquinoline-5-carboxamides are described. SCH351591 is a potent selective inhibitor of phosphodiesterase type 4 (PDE4).
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关键词
phosphodiesterase
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