Synthesis and cytotoxicity of diam(m)ineplatinum(II) complexes with 2,2-bis(hydroxymethyl)malonate as the leaving group.
Bioorganic & Medicinal Chemistry Letters（2012）
摘要
Complex 5 is more active and less toxic than its parent compound oxaliplatin.
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关键词
Platinum,2,2-bis(Hydroxymethyl)malonate,Synthesis,Anticancer activity
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