A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization

Shuwen He,Peng Li,Xing Dai,Casey C. McComas,Hongling Huang,Chaoliang Zhan,Liang Chang,Yuehui Liu,Shaojun Chen,Zhong Lai,Hong Liu,Jingjun Yin,Qun Dang,Dong Xiao,Nicolas Zorn,Xuanjia Peng,Ravi P. Nargund,Anandan Palani

Tetrahedron Letters（2013）

引用 13|浏览26

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摘要

We report a general method for the synthesis of the substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole ring system (structure 1) via the cyclization from an indoline precursor with aldehydes or ketones followed by oxidative re-aromatization.

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关键词

Indole,Indoline,Cyclization,6H-Pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole

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