The role of Litopenaeus vannamei p38 in white spot syndrome virus infection

Hong Shi,Lingwei Ruan,Xinfu Yan,Defu Yao,Xun Xu

Developmental & Comparative Immunology（2014）

引用 26|浏览45

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摘要

•Three closely related p38 MAPK homologues were cloned from Litopenaeus vannamei.•Three isoforms differ only in an internal 25-amino acid sequence.•lvp38a, lvp38b and lvp38c have different tissue expression patterns.•The activation of lvp38 took place in WSSV infection.•Silencing lvp38 promoted WSSV replication at the early stage.

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关键词

p38,Litopenaeus vannamei,WSSV,Gene silencing,Host defense

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