Low Copy Number of Mitochondrial DNA (mtdna) Predicts Worse Prognosis in Early-Stage Laryngeal Cancer Patients.

Alterations in mitochondrial DNA (mtDNA) copy number have been widely reported in various human cancers, and been considered to be an important hallmark of cancers. However, little is known about the value of copy number variations of mtDNA in the prognostic evaluation of laryngeal cancer.