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Biotransformation of testosterone and testosterone heptanoate by four filamentous fungi.

Steroids(2014)

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摘要
•Biotransformation of testosterone and testosterone heptanoate was investigated.•Four filamentous fungi were used for the biotransformation.•6β and 14α-hydroxytestosterone were obtained in biotransformation of testosterone heptanoate.•Androst-4-ene-3,17-dione was the major product in the biotransformation of testosterone.•Time course study was also carried out with four fungal species.
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关键词
Biotransformation,Testosterone heptanoate,Filamentous fungi,14α-Hydroxy testosterone,6β-Hydroxy testosterone
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