5-HT1B and other related serotonergic proteins are altered in APPswe mutation.

Walid Tajeddinn,Torbjörn Persson,Silvia Maioli,Javier Calvo-Garrido,Cristina Parrado-Fernandez,Takashi Yoshitake,Jan Kehr,Paul Francis,Bengt Winblad,Kina Höglund,Angel Cedazo-Minguez,Dag Aarsland

Neuroscience Letters（2015）

引用 13|浏览25

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摘要

•Both in vitro and ex vivo models with APPswe mutation are used.•5-HT1B and SERT expressions are reduced in APPswe models.•Previous report of reduced released 5-HT in AD models is confirmed.

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关键词

AD,5-HT,SERT,PS,SLC6A4,PET,GAPDH,IHC,APPswe,Tg2576,WT,ANOVA

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