Reply To Brunet And Doolittle: Both Selected Effect And Causal Role Elements Can Influence Human Biology And Disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA（2014）

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摘要

We agree with Brunet and Doolittle (1) on the utility of distinguishing the evolutionarily selected effects (SE) of some genomic elements from the causal roles (CR) of other elements that lack signatures of selection …

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computational biology,bioinformatics

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