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Microsatellite Repeats in Mitochondrial Genomes: A Bioinformatic Analysis

Proceedings of the 2015 International Conference on Advanced Research in Computer Science Engineering & Technology (ICARCSET 2015)(2015)

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摘要
Mitochondria also known as the powerhouses of the cells have their own DNA sequence and exhibit sequence similarity with bacterial genomes. Microsatellites are a special class of DNA repeats that are found to be helpful to understand evolution, diseases, and phylogeny are widely used in various applications including DNA Fingerprinting, Forensics, Paternity Studies and Linkage Analysis etc. These repeats are ubiquitously present in all genomes including mitochondrial genomes and very less is known about their distribution in organelle genomes. In this study, we have analyzed more than 4000 mitochondrial genomes and a detailed report on the distribution, frequency and variation of microsatellites in mitochondrial genomes has been presented.
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关键词
analysis,bioinformatics,distribution,genomes,microsatellites,mitochondria,repeats
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