Analysis and assessment of meperidine and normeperidine concentrations in urine]

In this study, urine concentrations of meperidine and normeperidine after a single therapeutic dose of meperidine in 5 healthy volunteers have been measured and compared the results to those in meperidine addicts. The results showed that there was a significant difference between two groups in the ratio of metabolite to parent drug. If can be concluded that the ratio should be aid in making a cause of meperidine injection.