Contribution of HPV sequences detection in cervical carcinoma screening]

At the present time, Human Papillomaviruses (HPV) is a leading cause of squamous intraepithelial lesions (SIL) and invasive carcinoma of the cervix. The aim of this article was to review the main taxonomic and epidemiologic data on HPV infection and to assess the potential clinical implications of the different HPV tests in staging women with borderline cytologies (ASC-US; ASC-H; LSIL); for follow-up after treatment of high-grade cervical intraepithelial neoplasia (CIN), for primary screening as the sole screening modality, or in association with cytology.