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The central role of CD4(+) T cells in the antitumor immune response.

JOURNAL OF EXPERIMENTAL MEDICINE, no. 12 (1998): 2357-2368

Cited by: 844|Views14
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Abstract

The induction of optimal systemic antitumor immunity involves the priming of both CD4(+) and CDB+ T cells specific for tumor-associated antigens. The role of CD4(+) T helper cells (Th) in this response has been largely attributed to providing regulatory signals required for the priming of major histocompatibility complex class I restricte...More

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