Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search
NATURE(2012)
摘要
The search for DNA homology is vital to recombinational DNA repair and occurs by intersegment contact sampling wherein the three-dimensional conformational state of the double-stranded DNA target and the length of the homologous RecA–single-stranded DNA filament have important roles.
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关键词
Biochemistry, Biophysics, Molecular biology
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